Quick Reference
- Scientific Rating
-
4.7/ 5.0
- Primary Mechanism
- NMDA receptor blockade and GABA agonism
- Standardized Form
- Magnesium bisglycinate chelate
Magnesium glycinate is a chelated form of magnesium bound to the amino acid glycine, a combination formulated specifically to improve absorption and reduce the gastrointestinal side effects associated with other magnesium salts. Magnesium itself is a cofactor in several hundred enzymatic reactions in the body, including those governing muscle relaxation, nerve transmission, and energy production. The glycine component is also believed to contribute independently to the compound's calming reputation, since glycine has its own recognized role in supporting sleep quality and nervous system regulation. This combination has made magnesium glycinate one of the preferred forms for evening or stress-support supplement formulations.
Table of Contents
Clinical Summary
A highly bioavailable, chelated form of magnesium bound to the relaxing amino acid glycine. It is critical for over 300 enzymatic reactions and is highly effective for improving sleep quality and reducing muscle cramps.
Dosage Guidelines
200-400mg of elemental magnesium daily, typically taken 1-2 hours before bedtime for sleep support.
Safety & Side Effects
Very gentle on the stomach compared to magnesium citrate or oxide, though exceptionally high doses may still cause loose stools.
Known Interactions
Can interfere with the absorption of bisphosphonates and certain antibiotics (such as tetracyclines and quinolones). Space doses by 2-4 hours.
Scientific References
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Medical Disclaimer
The information provided in this clinical review is for educational and informational purposes only. It is not intended to be a substitute for professional medical advice, diagnosis, or treatment.
*These statements have not been evaluated by the Food and Drug Administration (FDA). This product or ingredient is not intended to diagnose, treat, cure, or prevent any disease.
Always consult your physician or other qualified health provider with any questions you may have regarding a medical condition, or before beginning any new diet, fitness, supplement, or treatment regimen, especially if you have pre-existing medical conditions or are taking prescribed medications.
